Frontiers in Endocrinology · 2019

Analytical Verification Performance of Afirma Genomic Sequencing Classifier in the Diagnosis of Cytologically Indeterminate Thyroid Nodules

Yangyang Hao, Yoonha Choi, Joshua E. Babiarz, Richard T. Kloos, Giulia C. Kennedy, Jing Huang, P. Sean Walsh

Journal
Frontiers in Endocrinology · vol. 10
Published
4 Jul 2019

Synopsis

Analytical verification of the RNA sequencing-based Afirma GSC. Classifier calls were tolerant to variation in RNA input (5-30 ng) and to up to 75% dilution of malignant fine-needle aspirate material, and remained accurate in the presence of up to 75% blood or 30% genomic DNA. Kennedy is fifth of seven authors.

In the career genome

  • VeracyteChapter 10 · Strand B · Publication
    Veracyte, Inc.

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