Giulia KennedyPhD
Genome Research · 2004

Parallel Genotyping of Over 10,000 SNPs Using a One-Primer Assay on a High-Density Oligonucleotide Array

Matsuzaki H, Loi H, Dong S, Tsai YY, Fang J, Law J, Di X, Liu WM, Yang G, Liu G, Huang J, Kennedy GC, Ryder TB, Marcus GA, Walsh PS, Shriver MD, Puck JM, Jones KW, Mei R

Co-authorstrongly supportedWhole-genome genotyping platforms
Journal
Genome Research · vol. 14 · no. 3 · pp. 414-425
Published
2004

Synopsis

A high-throughput genotyping platform that uses a one-primer assay to genotype over 10,000 SNPs per individual on a single oligonucleotide array: restriction digestion fractionates the genome, a specific fractionated subset is amplified, and alleles are read by allele-specific hybridization to the array. The technical basis of the GeneChip Mapping 10K array; an erratum correcting a sequence followed in July 2004.

In the career genome

  • AffymetrixChapter 04 · Strand A · Company
    Affymetrix, Inc.

    Affymetrix

    Senior Director; led the Genomics Collaborations and Genotyping Technology R&D groups

    JAN 2000 – MAR 2008
  • AffymetrixChapter 05 · Strand B · Research
    Affymetrix, Inc.

    Whole-genome genotyping

    First author and co-author of the GeneChip Mapping array methods papers

    2003 – 2005