Genotyping over 100,000 SNPs on a pair of oligonucleotide arrays

Synopsis

A genotyping method for simultaneously scoring 116,204 SNPs on a pair of oligonucleotide arrays, with call rates above 99%, reproducibility above 99.97% and accuracy, measured by inheritance in trios and concordance with the HapMap Project, above 99.7%. Trade press summarised the Affymetrix sequence as "Kennedy et al. publishing in Nature Biotech in 2003 and Matsuzaki et al. publishing in Genome Research and Nature Methods in 2004", but no retrieved record shows the author list, so Kennedy's co-authorship is recorded as an open question.

In the career genome

• AffymetrixChapter 04 · Strand A · Company

  Affymetrix, Inc.

  Affymetrix

  Senior Director; led the Genomics Collaborations and Genotyping Technology R&D groups

  JAN 2000 – MAR 2008
• AffymetrixChapter 05 · Strand B · Research

  Affymetrix, Inc.

  Whole-genome genotyping

  First author and co-author of the GeneChip Mapping array methods papers

  2003 – 2005