Real-World Performance of the Afirma Genomic Sequencing Classifier (GSC)—A Meta-analysis

Synopsis

A meta-analysis of 13 independent real-world post-validation studies of the Afirma GSC, reporting sensitivity, observed specificity, observed positive predictive value and negative predictive value of 97%, 88%, 65% and 99%, compared with the 2018 validation study. Kennedy is listed as a co-author in an institutional record. The year is recorded as Veracyte lists it (2023); the Fox Chase record dates the paper 2022, and no journal or PubMed record was retrieved.