Thyroid · 2022

Preoperative Identification of Medullary Thyroid Carcinoma (MTC): Clinical Validation of the Afirma MTC RNA-Sequencing Classifier

Gregory W. Randolph, Julie Ann Sosa, Yangyang Hao, Trevor E. Angell, David C. Shonka, Virginia A. LiVolsi, Paul W. Ladenson, Thomas C. Blevins, Quan-Yang Duh, Ronald Ghossein, Mack Harrell, Kepal Narendra Patel, Michael H. Shanik, S. Thomas Traweek, P. Sean Walsh, Michael W. Yeh, Amr H. Abdelhamid Ahmed, Allen S. Ho, Richard J. Wong, Joshua P. Klopper, Jing Huang, Giulia C. Kennedy, Richard T. Kloos, Peter M. Sadow

Journal
Thyroid · vol. 32 · no. 9 · pp. 1069-1076
Published
Sep 2022

Synopsis

Clinical validation of the RNA-sequencing Afirma MTC classifier for medullary thyroid carcinoma: 100% sensitivity (21 of 21 MTC fine-needle aspirates called positive; 95% CI 83.9-100%) and 100% specificity (190 of 190 non-MTC aspirates called negative; CI 98.1-100%). Kennedy is twenty-second of twenty-four authors.

In the career genome

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